Dimethindene (When ATH D04AA13)

When ATH:
D04AA13

Characteristic.

Alkylamine derivative. The white crystalline powder;, bitter taste. It is soluble in water and alcohol.

Pharmacological action.
Antihistamine, antiallergic, protivozudnoe.

Application.

Inside - Endogenous itching (except pruritus in cholestasis), hives, eczema, allergodermatozı, pollen disease, nasal allergy, angioedema, food and drug allergy, allergic reactions during desensitization specific (Treatment and Prevention), exanthema in infectious diseases (rubella, kor, enable vetryanaya), insect bites, anaphylactic shock and serum sickness (adjuvant).

Outwardly - Pruritic dermatoses, hives, allergic reactions to insect stings, mild burns (solar, Household).

Contraindications.

Hypersensitivity, incl. other derivative alkylamine, the neonatal period (especially premature), pregnancy (I trimester).

Restrictions apply.

Zakrыtougolynaya glaucoma, bladder neck obstruction, benign prostatic hyperplasia, exacerbation of asthma, chronic obstructive pulmonary disease, pregnancy (II and III trimester), lactation, natural infancy (to 1 year).

Pregnancy and breast-feeding.

It contraindicated in I trimester of pregnancy, II and III trimester is possible only under strict indications, if the effect of therapy outweighs the potential risk to the fetus. Avoid the use of a gel in the I trimester of pregnancy, and in II-III trimesters - drawing on the vast surface of the body (particularly exudative and inflammatory). During the period of breastfeeding is not recommended in and applied to large areas of skin on the nipple (if the application is necessary, should stop breastfeeding).

Side effects.

From the nervous system and sensory organs: fatiguability, weakness, drowsiness (especially at the beginning of treatment), dizziness, seldom - a headache, excitation (especially in young children), sleep apnea (children under the age of 1 year).

From the digestive tract: dry mouth or throat, nausea, vomiting, rarely - a pain in the stomach, aggravation of gastric ulcer and duodenal ulcer.

Allergic reactions: rarely - allergic skin reactions.

Other: rarely - edema, rash, muscle spasm, in rare cases - disorders of the airways, the feeling of chest tightness.

When using the gel: rare - dryness and burning sensation at the site of application, in rare cases - skin rash and itching.

Cooperation.

Dampening effect on the central nervous system tranquilizers, hypnotic drugs and alcohol, Mr. holinoliticheskie effects of anticholinergic agents and tricyclic antidepressants (It increases the risk of elevated intraocular pressure). MAO inhibitors enhance the anticholinergic and CNS depressant effect.

Overdose.

Symptoms: CNS depression, drowsiness (mainly in adults), CNS excitation, ataxia, hallucinations, tonic-clonic seizures, midriaz, dry mouth, flushing, urinary retention and fever (mainly in children); gipotenziya, collapse.

Treatment: appointment of activated carbon, Saline laxatives, symptomatic therapy for cardio-vascular and respiratory systems (analeptic agents are not recommended).

Dosing and Administration.

Inside, adults and children over 12 years - 1-2 mg (20-40 Ml drops) 3 times a day, or 4 mg (1 caps.) 1 once a day (before bedtime); a single dose for children 1 Months before 12 years depending on the age, the multiplicity of reception - 3 once a day; the duration of treatment should not exceed 25 days.

Outwardly, a thin layer of gel is applied to affected skin 2-4 times a day.

Precautions.

Should not be used during the drivers of vehicles and people, skills relate to the high concentration of attention.

After application of the gel should avoid sun exposure of the treated areas of the skin. In pediatric patients is not recommended to apply the gel on the vast surface of the skin (particularly exudative and inflammatory).

Cautions.

With widespread skin lesions, the combination of local treatment with oral.