Adgelon solution for injections: instructions for using the medicine, structure, Contraindications

Active material: adgelon
When ATH: M09AX
CCF: Preparation, stimulates the regeneration of cartilage tissue
ICD-10 codes (testimony): M15
Manufacturer: ENDO-FARM AND PM UAB (Russia)

Adgelon solution for injections: dosage form, composition and packaging

Solution for intra-articular injection in the form of a transparent, colorless liquid, without smell.

1 ml
adgelon (0.01% solution glycoprotein in water for injection)10-9 ml

Excipients: sodium chloride, calcium chloride, water d / and.

2 ml – ampoule (6) – packings Valium planimetric (1) – packs cardboard.
2 ml – ampoule (10) – packings Valium planimetric (1) – packs cardboard.
2 ml – ampoule (6) – packs cardboard.
2 ml – ampoule (10) – packs cardboard.
2 ml – bottles (6) – packs cardboard.
2 ml – bottles (10) – packs cardboard.
5 ml – bottles (6) – packs cardboard.
5 ml – bottles (10) – packs cardboard.

Adgelon solution for injections: pharmachologic effect

Preparation, stimulates the regeneration of cartilage tissue. The active substance of the drug is a glycoprotein, isolated from bovine serum.

The adhesive interaction of cells modulate drug mezenhimnogo origin and ingibiruet peroxide oxidation of lipids. Contributes to the rapid accumulation of masses of young cartilage cells and their differentiation, that leads to more rapid formation of replacement cartilage, restoration of smooth articular surface in the area of damage and improve joint mobility. In applying the drug populates the area of damaged cells and restore cartilaginous young cartilage tissue in definitivnom form, tk. has a place of its differentiation into layers, inherent in the original gialinovomu cartilage. With intra-articular injections produced by the cells of cartilage main substance has a more streamlined structure: it becomes the same dense, as in the normal functioning of the cartilage tissue.

Use Adgelona® causes reduction of pain after 2-3 injection.

Adgelon solution for injections: pharmacokinetics

The farmakokinetike drug Adgelon® not provided.

Adgelon solution for injections: testimony

- Osteoarthritis of large joints.

Adgelon solution for injections: dosing regimen

The drug is indicated for intra-articular introduction. Solution imposed on 2 ml 2 times a week, a course of treatment – 5-10 injection.

Adgelon solution for injections: side effects

Side effects of the drug Adgelon® not disclosed.

Adgelon solution for injections: Contraindications

-infections of the skin and tissue at the site of application;

- Hypersensitivity to the drug.

Adgelon solution for injections: Pregnancy and lactation

Data on the use of drugs Adgelon® Pregnancy and lactation (breast-feeding) not provided.

Adgelon solution for injections: Special instructions

The simultaneous application Adgelona® with other drugs, solutions of antibiotics and CORTICOSTEROIDS. When combination therapy is recommended to comply with the time interval (few hours) between injections Adgelona® and other drugs.

Adgelon solution for injections: overdose

Currently, the cases of drug overdose Adgelon® not reported.

Adgelon solution for injections: drug interaction

Patient interaction drug Adgelon® with other drugs not covered.

Adgelon solution for injections: terms of dispensing from pharmacies

The drug is released under the prescription.

Adgelon solution for injections: terms and conditions of storage

The drug should be stored in a dry, protected from light, out of reach of children at a temperature of 4° c to 20° c. Shelf life – 2 year.

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