Depr

Published by
Vladimir Andreevich Didenko

Active material: dry standardized extract of St. John's wort
When ATH: N07XX
CCF: Phytopreparation with antidepressant activity
ICD-10 codes (testimony): F31, F32, F33, F41.2, N95.1
When CSF: 02.02.08.01
Manufacturer: LEK d.d. (Slovenia)

Pharmaceutical form, composition and packaging

Pills, coated green color, round, lenticular.

1 tab.
dry standardized extract of St. John's wort (Perforated Hypericus) 60 mg,
incl. gipericin (general) 300 g

Excipients: lactose, microcrystalline cellulose, talc, magnesium stearate, colloidal silicon dioxide.

The composition of the shell: hydroxypropyl, polyethylene glycol, talc, carnauba wax, Dyes: quinoline zheltыy (E104), indigotin (E132), Titanium dioxide (E171).

10 PC. – упаковки ячейковые контурные (3) – пачки картонные.

Deprim® forte

Capsules Solid, opaque, gelatin, green color; содержимое капсул – компактные гранулы, greenish-brown or grayish-brown color with a characteristic odor, size 0.

1 tab.
dry standardized extract of St. John's wort (Perforated Hypericus) 425 mg,
incl. gipericin (general) 1 mg

Excipients: lactose monohydrate, cellulose, calcium hydrogen phosphate dihydrate, colloidal silicon dioxide, magnesium stearate, talc, gelatin, sodium lauryl, water, Dyes (titanium dioxide E171, chlorophyll-copper complex E141), Purified water.

10 PC. – блистеры (3) – пачки картонные.

Pharmacological action

Sedativnый phyto. Основные активные вещества зверобоя – гиперицин, psevdogipericin, гиперфорин и флавоноиды – улучшают функциональное состояние центральной и вегетативной нервной системы.

Deprim® improves mood, normalizes sleep, enhances mental and physical activity.

Pharmacokinetics

The data on the pharmacokinetics Despres® not provided.

Testimony

- Depressed mood;

- Depression of mild to moderate severity, accompanied by anxiety (incl. associated with climacteric syndrome);

- Increased sensitivity to the weather.

Dosage regimen

Adults and children over 12 years appoint 1 tab. 3 times / day, or 1 capsule 1 time / day (regularly at the same time); if necessary, the dose may be increased to 2 capsules / day (in 2 admission). Children aged 6 to 12 years – под медицинским контролем по 1-2 tab. / day in the morning and afternoon.

Optimal effect is achieved when the drug taken regularly for several weeks. The therapeutic effect of the drug Despres® manifested later 10-14 days after start of.

Omitting one receiving the drug should be taken as soon as possible. If it is time for your next dose, should not take extra dose to compensate the missed reception. Do not take two doses at the same time.

The drug is taken orally, drinking water.

Side effect

From the digestive system: nausea, vomiting, constipation.

CNS: feeling tired, anxiety.

Allergic reactions: flushing of the skin, itching.

Dermatological reactions: in individuals with hypersensitivity to sunlight simultaneous reception of the drug and sunbathing can cause burns (photosensitivity).

Contraindications

- Severe depression;

- Children up to age 6 years (Pill, coated);

- Children up to age 12 years (Capsule);

- Hypersensitivity to the drug.

Pregnancy and lactation

Despite the lack of data on the harmful effects of the drug, reception Deprima® during pregnancy and lactation is possible only in case, if the expected benefit to the mother outweighs the potential risk to the fetus or child.

Cautions

Patients should be warned, that in the absence of therapeutic effect within 4-6 weeks after the start of treatment should stop taking Deprima® and contact your doctor.

Patients, receiving the drug, Avoid exposure to the sun and UV radiation (incl. solarium).

Patients, receiving the drug Despres®, should refrain from drinking alcohol.

Overdose

Symptoms: increased described side effects, generalized weakness, slackness, drowsiness.

Treatment: removal of the drug, Activated carbon.

Acute poisoning St. John's wort preparations in humans is not marked.

Drug Interactions

Deprim® activates the microsomal oxidation (Cytochrome P450), therefore, caution should be prescribed at the same time taking anticonvulsants, Antidepressants (serotonin reuptake inhibitors), tricyclic antidepressanov, MAO inhibitors, protivomigrenoznyh drugs (tryptanov), oral hormonal contraceptives, cardiac glycosides (incl. Digoxin), teofillina, cyclosporine, indinavir, reserpine.

In an application Despres® may potentiate funds for general anesthesia and opioid analgesics.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children at or above 25 ° C. Shelf life - 3 year.

Published by
Vladimir Andreevich Didenko

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