Dexamethasone (Eye drops)

Active material: Dexamethasone
When ATH: S01BA01
CCF: SCS for local application in ophthalmology
ICD-10 codes (testimony): H10.1, H10.2, H10.4, H10.5, (H) 15.0, (H) 15.1, H16, H16.2, H20.0, H20.1, H30, H46, S05, Z29.8
When CSF: 04.04.02
Manufacturer: WARSAW PHARMACEUTICAL WORK POLFA S.A. (Poland)

Pharmaceutical form, composition and packaging

Excipients: sodium hydrogen phosphate, sodium dihydrogen, sodium chloride, disodium edetate, benzalkonium chloride, polysorbate 80, ethanol, Purified water.

5 ml – dropper bottle plastic (1) – packs cardboard.

Pharmacological action

SCS for local application in ophthalmology. Anti-inflammatory, antiallergic and antiekssoudativoe action.

Active substance formulation – Dexamethasone – stabilizes cell membranes, reduces the permeability of capillaries, antiekssoudativoe action by stabilizing lizosom membranes.

Pharmacokinetics

The local application of dexamethasone permeates through rogovitsu with intact epithelium moisture in front of the camera eye.

Testimony

-acute and chronic allergic and inflammatory diseases of the eye (incl. conjunctivitis, scleritis, deep keratitis without damage to the epithelium, Irit, iridocyclitis, xorioidit, chorioretinitis, optic neuritis);

Prevention and treatment of inflammatory processes in the postoperative and Posttraumatic period.

Dosage regimen

Adults and children over 12 years at acute inflammatory processes the drug buried in the bag kongungualny by 1-2 drops 4-5 times / day for 2 days, then apply 3-4 times / day for 4-6 days.

At chronic processes the drug buried 2 times / day for 4 weeks. The maximum duration of the drug – 4 of the week.

IN postoperative and Posttraumatic periods Depending on the intensity of the inflammatory process, the drug buried 2-4 times / day for 1-2 drops within 2-4 weeks.

Children aged 6 to 12 years at treatment of allergic and inflammatory conditions instill 1 drop 2-3 times / day for 7-10 days. If necessary treatment continues after carrying out the 10th day of the fljuoresceinovoj samples (to verify the integrity of the corneal epithelium).

Before applying the skin should vesboltati.

Side effect

Local reactions: immediately after instillation of the drug may have momentary burning sensation. With long-term use may increase intraocular pressure (Therefore, when applying the preparations, containing kortikosteriody, more 10 days should regularly measure intraocular pressure).

When applying more 3 months may develop zadnekapsuljarnaja cataract. May slow regeneration processes.

Contraindications

- Keratit, caused by the Herpes simplex or Varicella zoster (tree keratitis), viral diseases cornea and conjunctiva (including when chicken pox);

-mikobakteriale eye infection;

-fungal diseases of the eye;

— acute fatigue eye disease;

— epiteliopatia of the cornea;

- Increased intraocular pressure;

- Hypersensitivity to the drug.

Pregnancy and lactation

The application of Dexamethasone in pregnancy and lactation (breast-feeding) possibly only, when the intended benefits to the mother outweighs the potential risk to the fetus or infant.

Cautions

Prolonged use of the drug can lead to secondary infection, caused by fungi or viruses.

When prolonged use of the drug also may increase intraocular pressure. Therefore, If the drug is used more 2 weeks, There is a need to control intraocular pressure.

Before applying the product soft contact lenses should be removed and install them again no earlier than 15 minutes after instillation of the drug.

With the development of infectious process may have simultaneous application of Dexamethasone with antibacterial drugs.

In developing allergic reactions use Dexamethasone should cease immediately.

Effects on ability to drive vehicles and management mechanisms

Taking into account the possibility of watering after instillation of drug, do not apply it directly to the Office or work with mechanisms.

Overdose

In overdose when applied topically Dexamethasone possibly worsening side effects.

Drug Interactions

Dexamethasone may intensify or weaken the effects of some drugs.

Perhaps the simultaneous use of Dexamethasone with midriatikami and drugs for systemic use (Vitamins, calcium supplementation, salicylates).

Conditions of supply of pharmacies

The drug is released under the prescription.

Conditions and terms

The drug should be stored in the dark, inaccessible to children at temperature from 15 ° to 25 ° C. Shelf life – 2 year. After opening bottle product can be used for a period of not more than 4 weeks.