Kalytsiya gluconate
When ATH:
A12AA03
Characteristic.
White granular or crystalline powder, odorless and tasteless. Slowly soluble in cold water (1:50), легко — в кипящей (1:5), practically insoluble in ethanol and ether. Contains 9% Calcium. Molecular weight 430,37.
Pharmacological action.
Antiallergic, detoxification, hemostatic, anti-inflammatory, reduces fragility and permeability of blood vessels.
Application.
Hypocalcemia, insufficiency of the parathyroid glands (latentnaya tetany, osteoporosis), metabolic vitamin D, rickets (spasmophilia, osteomalacia), Correction of hyperphosphataemia in patients with chronic renal failure, increased need for calcium (pregnancy, lactation, period of growth), insufficient intake of calcium from food, violation of calcium metabolism, incl. in post-menopausal, increased excretion of calcium (chronic diarrhea, secondary hypocalcemia, incl. against the background of long-term use of certain diuretics, anticonvulsant drugs or glucocorticoids), myasthenia (in the complex therapy), allergic diseases, bleeding, increased vascular permeability, parenchymal hepatitis, toxic liver damage, jade, eclampsia, poisoning magnesium salts, oxalic and hydrofluoric acid.
In dentistry: acute inflammation, accompanied by edema, postoperative period (to reduce edema), remineralization therapy for the prevention and treatment of caries and carious lesions of teeth, allergic diseases, prevention of postoperative bleeding.
Contraindications.
Hypersensitivity, hypercalcemia (концентрация кальция не должна превышать 12 mg% or 6 mEkv /), expressed hypercalciuria, calcium nefrourolitiaz, tromboflebit, thrombosis, sarkoidoz, concomitant use of cardiac glycosides (the risk of arrhythmias).
Restrictions apply.
Degidratatsiya, electrolyte abnormalities (the risk of hypercalcemia), diarrhea, malabsorption, calcium nefrourolitiaz (history), small hypercalciuria, moderate chronic renal failure, congestive heart failure, widespread atherosclerosis, hypercoagulation; для в/м введения — детский возраст (because of the risk of necrosis).
Side effects.
При приеме внутрь — запор, irritation of the gastrointestinal mucosa. При парентеральном введении — тошнота, vomiting, diarrhea, bradycardia; при в/в введении — ощущение жара сначала в полости рта, and then throughout the body; при в/м введении — инфильтраты и некроз в месте введения.
Cooperation.
Calcium gluconate complexes with tetracycline antibiotics and neutralizes their antibacterial effect when used together.
Dosing and Administration.
B /, / m, inside, locally, incl. by electrophoresis. Inside (before eating) 23 times per day: взрослым — 1–3 г и более; Children up to 1 year - 0,5 g, 2-4 Years - 1 g, 5–6 лет — 1–1,5 г, 7–9 лет — 1,5–2 г, 10–14 лет — 2–3 г. / M, in / in slowly over 2-3 min (solution previously warmed to body temperature) взрослым вводят по 5–10 мл 10% solution every day, a day or two days, depending on the evidence. Babies, w / w by slowly 1 to 5 ml 10% solution every 2-3 days depending on the age.
For remineralization therapy 10% solution in the form of applications or by electrophoresis for 10-15 min to the tooth surface.
Cautions.
Calcium gluconate is similar to the effect of calcium chloride, but has less irritating.