BYSTRUMGEL
Active material: Ketoprofen
When ATH: M02AA10
CCF: NSAIDs for outdoor use
ICD-10 codes (testimony): I80, M05, M54.3, M54.4, M65, M70, M71, T14.3
When CSF: 05.01.02
Manufacturer: Chemical-pharmaceutical plant AKRIKHIN OJSC (Russia)
Pharmaceutical form, composition and packaging
◊ Gel for external use 2.5% colorless, almost transparent, and odor; fluid light scattering experiment is allowed.
| 1 g | |
| Ketoprofen | 25 mg |
Excipients: ethanol (ethyl alcohol) rectified, nipagin, karʙomer, trometamol, Lavender, neroli oil, Purified water.
30 g – twbı (1) – packs cardboard.
50 g – twbı (1) – packs cardboard.
Pharmacological action
NSAIDs, propionic acid. It has analgesic, anti-inflammatory.
By inhibiting the Cox-1 and Cox-2, inhibits the synthesis of prostaglandins. Has antibradikininovoj activity, stabilizes the lysosomal membrane. Reduces the secretion of cytokines, inhibits the activity of neutrophils.
For articular syndrome, relieves pain in the joints at rest and during movement, reduces morning stiffness and swelling of joints, increases range of motion.
Pharmacokinetics
Absorption
При наружном применении геля происходит чрезвычайно медленное трансдермальное всасывание кетопрофена, which ensures that its concentration in inflamed tissues is maintained within a therapeutic level for a long time. Absorption into the systemic circulation is negligible. Virtually koumouliruet. Биодоступность геля около 5%.
Distribution
Ketoprofen well penetrates into synovial fluid and connective tissue.
Testimony
Воспалительные или травматические поражения суставов, tendons, ligaments and muscles:
- Arthritis, parasynovitis;
- Tendonitis, tendosynovyt;
— bursitis;
- bruises, damage to the ligaments, sprains, knee meniscus damage;
- torticollis;
- Lyumbago.
Phlebitis, periphlebitis.
Dosage regimen
The drug is applied to the skin of the painful area 2 times / day, squeezing out of the tube about 3-5 cm of gel or more (depending on the size of painful area), spread in an even thin layer and rub in gently until completely absorbed.
In order to increase the effectiveness of therapy, it is possible to use the gel under a dry occlusive dressing.
Side effect
In rare cases,: allergic reactions, which require discontinuation of the drug, photosensitivity.
Contraindications
- Dermatosis;
- Eczema;
- infected abrasions and wounds;
- Pregnancy;
- Lactation;
- Children's age;
- Hypersensitivity to ketoprofen or other ingredients.
Pregnancy and lactation
The drug is contraindicated during pregnancy and lactation.
Cautions
It is not recommended to apply the gel to open wounds or damaged areas of skin..
Нельзя допускать попадания геля на слизистые оболочки и в глаза.
Overdose
Случаев передозировки при применении препарата Быструмгель® not disclosed.
Drug Interactions
В настоящее время случаев лекарственного взаимодействия препарата Быструмгель® с другими лекарственными препаратами не выявлено.
Conditions of supply of pharmacies
The drug is resolved to application as an agent Valium holidays.
Conditions and terms
The drug should be stored in a dry, protected from light, inaccessible to children at temperature from 15 ° to 25 ° C. Shelf life – 2 year.
