Bisakodil
Active material: Bisakodil
When ATH: A06AB02
CCF: Laxatives, stimulating peristalsis
When CSF: 11.08.01
Manufacturer: ICN Polfa Rzeszów S.A.. (Poland)
DOSAGE FORM, COMPOSITION AND PACKAGING
◊ Pills, enteric coated Pink colour, round, lenticular.
1 tab. | |
bisakodil | 5 mg |
[Ring] potato starch, lactose, gelatin, talc (magnesium hydrosilicate), magnesium stearate.
The composition of the shell: cellacefat, shellac, polysorbate 20, sucrose kristallicheskaя, acacia gum, talc (magnesium hydrosilicate), carmine dye (Ponceau 4R).
30 PC. – blisters (1) – packs cardboard.
Pharmacological action
Laxative, diphenylmethane derivative. Increases of mucus secretion in the colon, It accelerates and enhances its peristalsis. The action is due to direct stimulation of nerve endings in the lining of the colon.
Pharmacokinetics
Bisacodyl is not absorbed from the gastrointestinal tract. It is a prodrug, in an alkaline medium is hydrolyzed to yield a compound, is irritating to the gastrointestinal mucosa.
Testimony
Constipation, due to hypotension and sluggish motility of the colon (in particular, elderly patients; constipation after surgery, delivery). Regulation stool hemorrhoids, proctitis, anal fissures. Preparing for surgery, instrumental and radiological studies.
Dosage regimen
Inside adults – by 5-15 mg, for children 8-14 years – by 10 mg, 2-8 years – by 5 mg. Reception frequency 1 just for the night or in the morning for 30 minutes before eating. Rectal adult – 10-20 mg; for children 8-14 years – by 10 mg, 2-7 years – by 5 mg.
Side effect
On the part of the digestive system: possible colicky pain in the intestines, diarrhea (It can lead to excessive loss of fluid and electrolytes and, Consequently, development of muscle weakness, seizures, hypotension).
Contraindications
Ileus, strangulated hernia, acute inflammatory diseases of the abdominal cavity, abdominal pain of unknown origin, peritonitis, bleeding from the gastrointestinal tract, uterine bleeding, cystitis, spastic constipation, acute proctitis, Acute Hemorrhoids.
Pregnancy and lactation
Bisacodyl used with caution during pregnancy and lactation (breast-feeding).
Cautions
To apply caution in patients with liver and kidneys.
Do not use for a long time.
Do not take simultaneously with milk and alkaline mineral water.
Drug Interactions
In an application may decrease the concentration of digoxin in the blood plasma.