Bikalutamid
When ATH:
L02BB03
Characteristic.
The white crystalline powder. Practically insoluble in water, poorly soluble in chloroform and alcohol, it is soluble in methanol, soluble in acetone.
Pharmacological action.
Antiandrogens, antitumor.
Application.
Prostate Cancer.
Contraindications.
Hypersensitivity, childhood, contraindicated for women.
Restrictions apply.
Abnormal liver function.
Pregnancy and breast-feeding.
Category actions result in FDA - X. (Animal tests or clinical trials revealed a violation of the fetus and / or there is evidence of the risk of adverse effects on the human fetus, obtained in research or practice; risk, associated with the use of drugs in pregnancy, greater than the potential benefits.)
Side effects.
Angina, hypertension, heart failure, cough, pharyngitis, bronchitis, pneumonia, rhinitis, dyspepsia, xerostomia, stomach bleeding, ground, alarm, depression, decreased libido, drowsiness, nervousness, myasthenia, myalgia, arthritis, jerking of the limbs, contractures, chest pain, diabetes, polyuria, dizurija, urinary retention, swelling, fever, Sweating, allergic reactions.
Cooperation.
Proximity effect anticoagulants.
Dosing and Administration.
Inside, regardless of the meal. Adults - 1 Table. (50 or 150 mg) single.
Cooperation
Active substance | Description of interaction |
Busulfan | FMR. Against the background of bicalutamide increases the risk of disease venookklyuzionnoy. |
Dakarʙazin | FMR. Against the background of bicalutamide enhanced risk of hepatotoxicity. |
Doxorubicin | FMR. Strengthens (mutually) the risk of toxicity |