Benzalkonium chloride

When ATH:
D08AJ01

Pharmacological action

Antiseptic. It is a quaternary ammonium compound, It refers to cationic surfactants. It has antimicrobial and antiviral activity against Neisseria gonorrhoeae, Chlamydia spp., Trichomonas vaginalis, Herpes simplex типа 2, Staphylococcus aureus, maloaktiven against Gardnerella vaginalis, Candida albicans, Haemophilus ducreyi и Treponema pallidum.

Not active against Mycoplasma spp.

It has a spermicidal effect, which is due to the ability to damage the membrane of sperm; inhibits sperm motility, disturbing the electrolyte balance of the aqueous phase of cervical mucus.

Pharmacokinetics

For external and local application is practically not absorbed.

Testimony

For outdoor use: antiseptic skin, mucosas, Wounds, seborrheic dermatitis.

For topical application,: vesicoclysis, urethra, irrigation of the vagina, contraception.

Disinfection of rooms and medical devices.

Dosage regimen

Individual, depending on the indication and dosage form.

Side effect

With prolonged use possible local irritation.

Contraindications

Hypersensitivity to benzalkonium chloride.

Pregnancy and lactation

It does not have any negative effect on pregnancy. Do not excreted in breast milk, It may be used during lactation.

Cautions

Benzalkonium chloride is incompatible with soaps and other anionic surfactants, and citrate, iodidami, nitratami, permanganates, salicylates, silver salts and tartrates.

Drug Interactions

The data is not provided.