BENFOLIPEN
Active material: Benfotiamin, Цianokoʙalamin, Pyridoxine
When ATH: A11DB
CCF: The complex B vitamins
ICD-10 codes (testimony): G50.0, G51, G60, G61, G62.1, G63.2, M54.1, M54.3, M54.4, M79.2
At KFU: 02.11.01
Manufacturer: OAO Pharmstandard-UfaVITA (Russia)
Pharmaceutical form, composition and packaging
Pills, Film-coated white or nearly white.
| 1 tab. | |
| ʙenfotiamin | 100 mg |
| pyridoxine hydrochloride (wreathed. B6) | 100 mg |
| цianokoʙalamin (wreathed. B12) | 2 g |
Excipients: karmelloza (carboxymethyl cellulose), povidone (Kollidon 30), microcrystalline cellulose, talc, calcium stearate (calcium octadecanoate), polysorbate 80 (Tween 80), sucrose.
The composition of the shell: giproloza (hydroksypropyltsellyuloza), macrogol (polyethylene oxide 4000), povidone (low molecular weight polyvinyl Medical), Titanium dioxide, talc.
15 PC. – packings Valium planimetric (2) – packs cardboard.
15 PC. – packings Valium planimetric (4) – packs cardboard.
Pharmacological action
Combined multivitamin complex. Effect of the drug is determined by the properties of vitamins, its constituent.
Benfotiamin – fat-soluble form of thiamine (vitamin B1), participates in the nerve impulse.
Pyridoxine hydrochloride (vitamin B6) is involved in the metabolism of proteins, carbohydrates and fats, It is necessary for normal hematopoiesis, functioning of the CNS and peripheral nervous system. It provides synaptic transmission, inhibitory processes in the CNS, involved in the transport of sphingosine, a member of the nerve sheath, involved in the synthesis of catecholamines.
Цianokoʙalamin (vitamin B12) involved in the synthesis of nucleotides, It is an important factor for normal growth, blood formation and development of epithelial cells; necessary for the metabolism of folic acid and synthesizing myelin.
Pharmacokinetics
Data on the pharmacokinetics Benfolipen® no.
Testimony
It is used in the treatment of these neurological diseases:
- Neuralgia nerve troynichnogo;
- Neuritis of the facial nerve;
- Pain, caused by diseases of the spine (incl. mezhrebernaya neuralgia, ljumʙoişialgija, lumbar syndrome, cervical syndrome, neck and shoulder syndrome, radicular syndrome, caused by degenerative changes of the spine);
- Polyneuropathy of different etiologies (Diabetic, Alcoholic).
Dosage regimen
The drug should be taken after meals, liquid squeezed small amounts of liquid.
Adults appoint 1 tab. 1-3 times / day.
Course Length – on doctor's advice. Not recommended treatment with high doses of the drug over 4 weeks.
Side effect
Allergic reactions: itching, urticaria.
Other: in some cases – increased perspiration, nausea, tachycardia.
Contraindications
- Severe and acute forms of decompensated heart failure;
- Children's age;
- Hypersensitivity to the drug.
Pregnancy and lactation
Benfolïpen® It contains 100 mg of vitamin B6 so during pregnancy and lactation (breast-feeding) drug use is not recommended.
Cautions
During the administration of the drug is not recommended to take multivitamin complexes, containing B vitamins.
Overdose
Symptoms: increased symptoms of side effects of the drug.
Treatment: gastric lavage, administration of activated charcoal, appointment of symptomatic therapy.
Drug Interactions
Levodopa reduces the effects of therapeutic doses of vitamin B6.
Vitamin B12 incompatible with salts of heavy metals.
Ethanol dramatically reduces the absorption of thiamine.
Conditions of supply of pharmacies
The drug is released under the prescription.
Conditions and terms
The drug should be stored in a dry place protected from light, reach of children, at a temperature not higher 25 ° C. Shelf life – 2 year.
