Avenue - instructions for use of the drug, structure, Contraindications
Avenue ® has a venotonic and angioprotective effect, increases venous tone, reduces vein extensibility and venous stasis, improves microcirculation, It reduces capillary permeability and increase their resistance, improves lymphatic drainage, increasing lymph flow.
Avenue: indications and dosage
Indications of the drug Avenue:
Symptomatic treatment of venolymphatic insufficiency (heaviness in the legs, pain, swelling).
Symptomatic treatment of hemorrhoids.
For oral administration. Assigned to adults.
Treatment of venolymphatic insufficiency (symptoms: swelling, pain, heaviness in the legs, night cramps, sores, lymphedema)
The recommended dose is 2 tablets per day 1 tablet – afternoon and 1 tablet – in the evening, while eating. After a week of use, you can take 2 tablets once a day with meals.
Treatment of chronic hemorrhoids .
By 2 tablets per day (in two receptions) while eating. After a week of use, you can take 2 tablets once a day with meals.
Treatment of acute hemorrhoids.
By 6 tablets per day for 4 days, then 4 tablets per day for the next 3 days. Apply with meals. Divide the daily number of tablets by 2-3 admission.
A course of treatment. The duration of treatment depends on the indications for use and the course of the disease.. The average duration of treatment is 2-3 of the month.
Children.
Data on the use of the drug Avenue ® children are missing.
Avenue: overdose
No cases of overdose with Avenue have been reported..
Avenue: side effects
Adverse reactions of the drug Avenue:
From the nervous system: dizziness, headache, malaise.
From the gastrointestinal tract: diarrhea, dyspepsia, nausea, vomiting, colitis.
Skin and subcutaneous tissue disorders: rash, itch, hives, isolated swelling of the face, lips, century, angioedema.
Avenue: Contraindications
Hypersensitivity to the active substance or to any of the excipients of Avenue.
Avenue: interactions with other drugs and alcohol
Interaction studies with Avenue have not been conducted.. However, there is a large post-registration experience with the use of diosmin., and interactions with other medicinal products have not yet been reported.
Avenue: composition and properties
active substance: 1 tablet contains 500 mg micronized purified flavonoid fraction (in terms of 100% anhydrous substance), which contains 450 mg diosmin (90%) and 50 mg flavonoids as hesperidin (10%);
Excipients: polyvinyl alcohol, microcrystalline cellulose, sodium starch (Type A), talc, magnesium stearate, Opadry II 85F34486 Pink (polyvinyl alcohol, Titanium dioxide (E 171), polyethylene glycol (macrogol), talc, iron oxide red (E172) , iron oxide yellow (E172)).
Product form: Pills, Film-coated.
Avenue: pharmachologic effect:
Farmakodinamika.
Avenue ® has a venotonic and angioprotective effect, increases venous tone, reduces vein extensibility and venous stasis, improves microcirculation, It reduces capillary permeability and increase their resistance, improves lymphatic drainage, increasing lymph flow.
The drug also reduces the interaction of leukocytes and endothelium, adhesion of leukocytes in postcapillary venules. This reduces the damaging effect of inflammatory mediators on the walls of the veins and the cusps of the valves of the veins..
Pharmacokinetics.
The half-life of 11:00.
The excretion of the active substance occurs mainly through the intestines.. Excreted via urine on average 14% dose.
Storage conditions: Store Avenue in its original packaging at a temperature not exceeding 25 ° C. Keep out of the reach of children.
Avenue: general information
- Sales form: over-the-counter
- Current in-about: Hesperidin
- Manufacturer: Farmak, JSC, Kiev City, Ukraine
- Farm. Group: Cardiovascular drugs
