Autoimmune hepatitis – what is this, treatment of disease, symptoms and prevention of autoimmune hepatitis

Аутоиммунный гепатит – что это за болезнь? Autoimmune hepatitis (or chronic active hepatitis) -liver disease, in which the destruction of her own immune system cells. This disease has a tendency toward rapid progression, that could lead to the development of liver cirrhosis. In this case, the symptoms can resemble the system red Lupus.

Autoimmune hepatitis: the cause of the

Autoimmune hepatitis is a rather rare disease, and the reasons for its development is currently still unknown.

There is a version, This pathology can develop infection by some viruses. In particular, there is evidence, What is autoimmune hepatitis develops after viral hepatitis a, And C, After herpes infection, and after infection Epstein-Barr.

Autoimmune hepatitis: autoimmune hepatitis symptoms

Approximately 25% disease patients are asymptomatic. Possible symptoms of autoimmune hepatitis can be:

• · Increased fatigue;
• · A fever of body temperature;
• · increased liver;
• · Jaundice;
• · Pain and discomfort in the right hypochondrium;
• · Lymphadenopathy;
• · Acne disease;
• · Kushingoid;
• · Excessive growth;
• · Isolated ascites;
• Pain in the right hypochondrium;
• · Other symptoms.

Autoimmune hepatitis: diagnostics

Diagnosis of autoimmune hepatitis involves:

• Pain in the right hypochondrium, physical examination of the patient;
• Clinical blood clinical, biochemical blood analysis, coagulogram, immunological blood test, a blood test for the presence of hepatitis viruses;
• coprogram, feces analysis for helminth eggs;
• examination of feces for the presence of helminths and protozoa, esophagogastroduodenoscopy;
• Computed tomography of the abdominal organs, roasted biopsy, elastography;
• · other research methods (at the discretion of the physician).

Autoimmune hepatitis: classification

There are several types of autoimmune hepatitis, among which:

• · Autoimmune hepatitis 1 -antibodies to fibres smooth muscles and antinuclear antibodies;
• · Autoimmune hepatitis 2 type-mikrosomam antibodies to liver and kidney cells;
• · Autoimmune hepatitis 3 -antibodies to soluble hepatic Antigen.

Each type of autoimmune hepatitis has its particular manifestation and treatment.

Autoimmune hepatitis: patient actions

In identifying host one or more of the above symptoms should consult a physician-gastroenterologist. The sooner you seek medical help, the higher the chances for successful treatment.

Treatment of autoimmune hepatitis

When autoimmune hepatitis patient is assigned a diet number 5.

Conservative treatment of this condition involves the application of the following drugs:

• gljukokortikosteroidnye hormones;
• immunosuppressants;
• combined application of glucocorticoids and immunosuppressants;
• preparations of Ursodeoxycholic acid (ursohol).

Indicators of the effectiveness of the treatment can be considered stihanie symptoms, normalization of the clinical picture, The histological pattern and biochemical parameters.

Surgical treatment for autoimmune hepatitis is performed with the ineffectiveness of medical treatment, frequent relapses and complications from drug therapy. Surgical treatment of liver transplantation envisages. The most commonly performed transplant part of the liver from a close relative.

Autoimmune hepatitis: complications

Complications of autoimmune hepatitis can be:

• cirrhosis of the liver;
• the defeat of other bodies (yazvennыy colitis, diabetes, gemoliticheskaya anemia, pleurisy, polyarthritis, glomerulonephritis, polimiozit, perikardit, miokardit, gipereosinofilny syndrome, cutaneous vasculitis and other).

Prevention of autoimmune hepatitis

Primary prevention of autoimmune hepatitis is not designed. For the secondary prevention of the disease include timely medical examination of patients for the purpose of early detection of this disease.