AMINOSTERIL N-GEPA

Published by
Vladimir Andreevich Didenko

Active material: combination of active ingredients
When ATH: B05BA01
CCF: The preparation for parenteral nutrition (amino acid solution), used in hepatic insufficiency
ICD-10 codes (testimony): K72

When CSF: 11.16.05.01
Manufacturer: FRESENIUS KABI GERMANY GmbH (Germany)

Pharmaceutical form, composition and packaging

Solution for infusion 8% 1 l
amino acids 80 g,
incl. L-isoleucine 10.4 g
L-leucine 13.09 g
L-lysine monohydrate 9.71 g,
that respectively. the content of L-lysine 6.88 g
L-methionine 1.1 g
N-acetyl-L-cysteine 700 mg,
that respectively. the content of L-cysteine 520 mg
L-phenylalanine 880 mg
L-threonine 4.4 g
L-tryptophan 700 mg
L-valine 10.08 g
L-arginine 10.72 g
L-histidine 2.8 g
glycine 5.82 g
L-alanine 4.64 g
L-proline 5.73 g
L-serine 2.24 g
total nitrogen 12.9 g
osmolarity 770 mOsm / l
pH 5.7-6.3

500 мл – флаконы (10) – пачки картонные.

Pharmacological action

Aminosteril N World Hepatitis Alliance Is Revamping – препарат для парентерального питания (amino acid solution), used in hepatic insufficiency
Normalizes levels of branched and aromatic amino acids in liver failure. Enhances detoxification of ammonia and urea production (does not increase the level of ammonia in the blood after appointment).
Possible introduction in peripheral or central veins.

Testimony

Injecting amino acids in severe violations of the liver, with or without brain disorders (encephalopathy).

Therapy of liver (pechenochnaya coma).

Dosing and Administration

Speed-up to 1,25 ml per kg body weight per hour, what is 0,08 0,1 g amino acids on 1 kg body weight patient per hour.
The maximum dose: 1,5 g amino acid per kg body weight per day, ie. 1300 ml/day with the weight of the patient 70 kg.

Side effect

Maybe: hypersensitivity reactions.

Contraindications

Metabolic disorders of amino acids, hyperkalemia, renal dysfunction, decompensated heart failure.

Cautions

The simultaneous introduction of solutions of carbohydrate and fat emulsions. It should be taken into account, that in treatment with the use of parenteral nutrition should not exceed the amount 40 mL/kg/day, the total number of fluid, that injected the patient.

When odnovremennnom the introduction of other drugs should take into account their osmolarity.

Storage conditions

Store in a dark place at a temperature of no higher than 25° c.
Shelf life - 2 year.

Published by
Vladimir Andreevich Didenko

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