Algeldrat

When ATH:
A02AB02

Pharmacological action

Antacid. Neutralize the excess hydrochloric acid, without causing secondary hypersecretion. It has absorbent and protective action. Relieves heartburn and pain in giperatsidnyh states.

Pharmacokinetics

Абсорбция – низкая.

Testimony

Gastric ulcer and duodenal ulcer in the acute phase, acute gastritis, hyperacid gastritis, erosive and ulcerative ezofagogastroduodenit, hastroэzofahealnыy reflux, hiatal hernia, functional intestinal lesions, colitis, heartburn, discomfort, epigastric pain, when errors in the diet.

Dosage regimen

Establish individually. In diseases of the esophagus, stomach or duodenum take medication after eating, при заболеваниях кишечника – до еды.

Side effect

From the digestive system: constipation, change in taste, nausea, vomiting, diarrhea.

From the laboratory parameters: при длительном применении в высоких дозах – повышение концентрации алюминия в крови, gipofosfatemiя, hypocalcemia.

From the urinary system: renal failure; при длительном приеме в высоких дозах – гиперкальциурия, impairment of renal function, nephrocalcinosis; у больных с сопутствующей почечной недостаточностью – жажда, decrease in blood pressure, giporefleksiя.

Other: при длительном применении в высоких дозах – остеомаляция, osteoporosis, encephalopathy.

Contraindications

Renal failure, Alzheimer's disease, gipofosfatemiя, pregnancy, Hypersensitivity to algeldratu.

Cautions

To use caution in renal disease. In patients with renal insufficiency during treatment may algeldrata thirst, decrease in blood pressure, giporefleksiя.

Do not use in patients with a higher concentration of aluminum in the blood (a risk factor for the development or worsening of the disease of Alzheimer's), and constipation.

With prolonged use is necessary to ensure intake of sufficient amounts of phosphorus.

The absorption of aluminum increases while receiving acidic beverages (fruit juices, wine).

Drug Interactions

Preparations aluminum, which are used as antacids, interact with most medicines for oral administration either by adjusting the pH of gastric juice and rapid gastric emptying, or by adsorption to form complexes, that are not absorbed.

With simultaneous use of citrate, ascorbic acid increases absorption of aluminum from the gastrointestinal tract.