Alklometazon

When ATH:
D07AB10

Characteristic.

Alclomethasone dipropionate - white powder, insoluble in water, slightly soluble in propylene glycol, sparingly soluble in hexylene glycol.

Pharmacological action.
Glucocorticoid, anti-inflammatory, antiallergic, antiproliferative, protivopsoriaticheskoe, protivozudnoe.

Application.

Dermatitis (atopic, pin, etc..) the localization process in sensitive areas (face, skin folds) or in people with sensitive skin (older children 1 , the elderly and patients), psoriasis, hives, itching in allergic diseases.

Contraindications.

Hypersensitivity, lupus, enable vetryanaya, perioral dermatitis, Rosacea, complications after vaccination, Age to 1 year.

Pregnancy and breast-feeding.

Maybe (for a short time and at low surface), if the effect of therapy outweighs the potential risk to the fetus.

Category actions result in FDA - C. (The study of reproduction in animals has revealed adverse effects on the fetus, and adequate and well-controlled studies in pregnant women have not held, However, the potential benefits, associated with drugs in pregnant, may justify its use, in spite of the possible risk.)

Be particularly careful when using in nursing mothers, incl. can not be applied to the skin of the breast before feeding.

Side effects.

Rarely (1-2% Of, mainly in the use of occlusive dressings) - burning sensation, itch, redness, irritation and dryness of the skin, ugrevidnye rashes; very rarely - acne, gipopigmentatsiya, jerseys, folliculitis, striae, atrophy of the skin and subcutaneous tissue, hypertryhoz, contact type allergy, Secondary skin infections; in a few cases (with prolonged use and / or applied to large areas) - development of systemic side effects (suppression and insufficiency of the adrenal cortex).

Overdose.

Symptoms: giperglikemiâ, glikozuriâ, inhibition of the function of the adrenal cortex, growth retardation, the syndrome itsenko-Kushinga.

Treatment: removal of the drug, simptomaticheskaya therapy.

Dosing and Administration.

Locally. Apply a thin layer to the affected skin, gently rubbing, 23 times per day.

Precautions.

It should not be long-term use on large areas of skin and use of occlusive dressings, tk. may increase bone resorption and systemic side effects (infants skin folds and diaper can mimic the action of occlusive dressings). In the children's age and hepatic dysfunction is necessary to periodically test for free cortisol in the urine and ACTH stimulation test. Do not apply to eyes or skin in the immediate vicinity (provokes the development of glaucoma and cataracts). In the case of secondary bacterial or fungal infection and prescribe antimicrobials to decide whether to abolish therapy.