Naftifin

When ATH:
D01AE22

Characteristic.

The antifungal agent for topical use.

Naftifina hydrochloride is a synthetic derivative of allilamina, the molecular weight is 323,86.

Pharmacological action.
Antifungal.

Application.

Fungal skin lesions and skin folds (including athlete's hands and feet, particularly those caused by Epidermophyton floccosum, trihofitii, incl. caused Trichophyton rubrum and Trichophyton mentagrophytes), onixomikoz, candidiasis of skin, pityriasis (variegated) lichen, fungal infections with secondary bacterial infection; mycosis of the external auditory meatus (for a solution for outdoor applications).

Contraindications.

Hypersensitivity (incl. to propilenglikolu-for solution, benzilovomu alcohol — for cream); applying to the surface of an open wound (for a solution).

Restrictions apply.

Childhood (safety and effectiveness in children have not identified).

Pregnancy and breast-feeding.

Teratogenic effects. In reproduction studies in rats and rabbits when administered in doses into naftifine, in 150 or more times higher than the dose for humans by topical application, there was no significant impaired fertility or harm to the fetus, caused naftifine.

When pregnancy is with caution (adequate and well-controlled studies in pregnant women have not performed).

Category actions result in FDA - B. (The study of reproduction in animals revealed no risk of adverse effects on the fetus, and adequate and well-controlled studies in pregnant women have not done.)

Unknown, Do naftifine penetrates into breast milk. Because many drugs are excreted into the milk of women, Caution should be exercised when used during breastfeeding.

Side effects.

Local reactions: xerosis, redness, burning, itch, irritation.

Dosing and Administration.

Outwardly. Is used in the form of a cream (1%) or solution (1%). In dermatomikozah-mark on the infested area and surrounding skin areas, previously cleaned and dried, 1 once a day. Duration of treatment when dermatomikozah — 2-4 weeks; If candidiasis is not less than 4 Sun; If necessary, extend to 6-8 weeks. In the absence of clinical improvement after 4 Weeks application is recommended to specify the diagnosis. In onihomikozah-cream or solution are depressed at the surface, covering tight bandage, 2 once a day, Course - 6 Months; complications of forms — to 8 Months. To prevent recurrence treatment continued for a further 2 weeks after the clinical improvement.

Precautions.

Use only externally. Avoid contact with mucous membranes of the eyes, nose, mouth etc.. Do not use air-tight bandage or wrap the affected surfaces without consulting a doctor. If you have any signs of hypersensitivity treatment cancel.