Active material: Sulbutyamyn
When ATH: A11DA02
CCF: Preparation, used in asthenic conditions
ICD-10 codes (testimony): F48.0
When CSF: 16.11
Manufacturer: Les Laboratoires Servier (France)


Pills, coated orange, round, lenticular, Slight surface heterogeneity (on the degree of gloss), staining and the presence of small inclusions.

1 tab.
sulbutyamyn200 mg

Excipients: corn starch, krahmalynaya paste vыsushennaya, dextrose bezvodnaya, lactose monohydrate, magnesium stearate, talc, natriya carbonate, sodium carboxymethylcellulose, white beeswax, Titanium dioxide (E171), ethyl cellulose, yellow dye (Sunset yellow FCF, E110), glycerol monooleate, polysorbate 80, povidone, sucrose, Colloidal anhydrous silica.

10 PC. – blisters (2) – packs cardboard.
15 PC. – blisters (4) – packs cardboard.


Pharmacological action

Synthetic compounds, similar in structure to thiamine. The molecule has an open sulbutiamine thiazole ring, additional disulfide bond and lipophilic ester. With this modification is rapidly absorbed from the gastrointestinal tract and readily crosses the blood-brain barrier.

Unlike thiamine, can accumulate in the cells of the reticular formation, hippocampus and dentate gyrus, as well as in the cells of Purkinje fibers and the glomeruli of the granular layer of the cerebellar cortex.

While taking Enerion improves coordination of movements and increases resistance to physical stress, increases the stability of the structures of the cerebral cortex to repetitive hypoxia.




Once inside sulbutiamine rapidly absorbed from the gastrointestinal tract, Cmax plasma levels achieved after 1-2 no.


T1/2 is about 5 no. Excreted in the urine.



- Symptomatic treatment functional asthenia.



Adults drug administered in a daily dose 400-600 mg (2-3 tab.) in 2 admission.

The tablets should be taken orally at breakfast and at lunch.

The duration of treatment should not exceed 4 weeks.



CNS: tremor, headache, excitation, general malaise.

From the digestive system: dyspepsia.

Allergic reactions: possible skin manifestations.



- Hypersensitivity to the drug.


Pregnancy and lactation

According to the results of clinical trials on the drug does not affect fetal development. Nonetheless, due to the lack of sufficient clinical data Enerion not recommended during pregnancy and lactation (breast-feeding).



Do not appoint Enerion patients with lactase deficiency, galactosemia or syndrome glucose / galactose malabsorption due to the fact, that the drug includes lactose monohydrate.

Use in Pediatrics

The drug is not recommended children and adolescents under the age of 18 years due to lack of clinical evidence.

Effects on ability to drive vehicles and management mechanisms

The drug does not affect the ability to drive vehicles and management mechanisms.



Symptoms: possibly with symptoms of excited state of euphoria and tremor of limbs.

Treatment: symptoms quickly disappear on their own and do not require special treatment.


Drug Interactions

Drug interaction is absent.


Conditions of supply of pharmacies

The drug is released under the prescription.



The drug should be stored out of reach of children at or above 25 ° C. Shelf life – 3 year.