Gastric ulcer – treatment of disease. Symptoms and prevention of diseases of a stomach ulcer

Gastric ulcer – What is this disease? Stomach ulcer (Ulcus gastrica) is a chronic pathologic process, based on the inflammation of the mucous membrane of the stomach (often an infectious nature), as a consequence the local mucosal defect is generated as a response to the internal imbalance of local factors "protection" and "aggression".

This disease is most common among diseases of the digestive tract.

Gastric ulcer – The cause of the

The main etiological factors of this pathology are following:

• infection of Helicobacter pylori;
• alimentary factor;
• unfavorable psychoemotional background;
• excessive drinking coffee, alcohol, smoking;
• acceptance of certain medicines (non-steroidal anti-inflammatory drugs, gljukokortikosteroidov, reserpine);
• some concomitant diseases (cirrhosis of the liver, cardiovascular diseases, leading to hypoxia and ischemia of other bodies, diseases of the pancreas, bronchial asthma, COPD, emphysema).

Risk factors for peptic ulcer disease can be divided into modifiable (stress, diet features, bad habits, party preparations) and non-modifiable (genetic predisposition), namely:

• family giperpepsinogenemija;
• high titer of antibodies to sekretornomu and immunoglobulinu;
• hyperthyroidism and hypertrophy of G-cells in the antrum of the stomach Division;
• high titer antibodies to parietal cells;
• rare genetic syndromes (amiloidoz, systemic mastocytosis, Multiple Endocrine adenoma).

Symptoms of gastric ulcers

Clinical symptoms of peptic ulcer disease depend on the stage of the disease process, the patient's age, comorbidity. You can select the following symptoms:

• pain syndrome (pain occurs some time after the meal, that is associated with a greater concentration of hydrochloric acid in the stomach, reduced through 1,5-2 o'clock);
• dyspepsia (nausea, heartburn, burp air or sour stomach contents, vomiting, brings relief, a sense of gravity in epigastralna area, feeling quick saturation);
• eating disorders (decrease or increase);
• asthenoneurotic syndrome;
• weight loss.

Gastric ulcer – Diagnostics

The gold standard for diagnosing stomach ulcers is esophagogastroduodenoscopy with biopsies. But, It is equally important to diagnose for infection n. rulori. For this purpose there are non-invasive (breathing test, serology, kalovyj Antigen test) and invasive (morphological, bacteriological method, urease test, PCR) methods. Also used the study's factional stomach contents, Intragastric pH-Metry, radiography of abdominal cavity organs, fecal occult blood test. Biochemical blood analysis are also, Ultrasonography of the abdomen, coagulogram.

Gastric ulcer – Classification

On the etiology of gastric ulcer is divided into:

• HP-associated ulcer;
• HP-neassociirovannuju peptic ulcer;
• stress;
• drug;
• idiopaticescuu;
• associated with endocrine pathology (giperparatireozom, Zollinger Ellison Syndrome);
• disease-related internals (cirrhosis of the liver, COPD, Heart Failure);
• mixed (HP + and other causative factor at the same time).

Secrete several stages of pathological process:

• Active (acute);
• rubcujushhajasja;
• stage of the scar;
• not long rubcujushhajasja ulcer.

Gastric ulcer – Actions of the patient

The main task of the patient-compliance with nutrition, abandon bad habits and to comply with doctor's appointments.

Treatment of gastric ulcers

• Therapeutic tactics really depends on, whether the patient is infected with modern. Peptic ulcer, associated with HP, "triple antihelikobakterna" schema therapy, that includes Proton pump inhibitor (omez, nol'paza etc), clarithromycin and amoxicillin (or metronidazole). Therapy continues 7-14 days. The second line therapy is a classic kvadroterapija with the addition of bismuth subcitrate. The ineffectiveness of the first two treatment regimens apply one of the options "rescue therapy»:
• Proton pump inhibitor (IPP) + high dose amoxicillin- 10-14 days;
• · IPP + amoksiцillin + levofloxacin (or rifabutin) – 7-10 days;
• · IPP + tetracycline + vysmut + furazolidone is for 7 Nights.

The most successful method of therapy is determined by the sensitivity test (H). Pylori.

When Hp-associated ulcers treatment consists in the appointment of antisecretory agents (IPP, Bismuth subcitrat), Antacids and adsorbents (Aluminium phosphate gel), preparations, improve the regenerative processes in gastric mucosa, phytotherapy, invalid food.

To monitor the effectiveness of treatment recommended for re-EXAMINATION through 3 and by 6 months after a course of therapy.

Oslozhnjonnye ulcers often require surgical intervention.

Gastric ulcer – Complications

• perforated ulcer;
• gastrointestinal bleeding;
• malignization ulcers (malignant);
• penetration of ulcer (spread beyond the stomach ulcers);
• stenosis pryvratnyka;
• periviscerity.

Prevention of stomach ulcers

You can improve the emotional condition of the patient, combating addictions, normalization of diets and maintaining a qualitatively good nutrition, as well as the timely treatment of chronic gastritis.