TERZHINAN

Active material: combined preparation
When ATH: G01BA
CCF: With antibacterial drug, antiprotozoal, anti-fungal and anti-inflammatory action for local application in gynecology
Codes ICD-10 (testimony): A59, B37.3, N76, Z29.2
When CSF: 04.04.04
Manufacturer: Laboratoires Bouchara-RECORDATI {France}

Pharmaceutical form, composition and packaging

Tablets for vaginal application	1 tab.
ternidazol	200 mg
neomycin sulfate	100 mg
Nystatin	100 tys.ED
prednisolone	3 mg

Excipients: corn starch, lactose, silicon dioxide, anhydrous, talc, magnesium stearate, sodium lauryl, povidone, perfume.

6 PC. – упаковки ячейковые контурные (1) – пачки картонные.
10 PC. – упаковки ячейковые контурные (1) – пачки картонные.

Pharmacological action

Combined preparation for local application in gynecology. The action of the drug due to the properties of its components.

Тернидазол – производное имидазола – оказывает трихомонацидное действие, It is also active against Anaerobic bacteria, in particular Gardnerella spp.

Неомицина сульфат – антибиотик широкого спектра действия из группы аминогликозидов.

Нистатин – противогрибковый антибиотик из группы полиенов, highly active against fungi of the genus Candida.

Преднизолон – глюкокортикоид, It has a pronounced anti-inflammatory effect.

The composition of the excipient ensures the integrity of the vaginal mucosa and persistence of pH.

Pharmacokinetics

Research pharmacokinetics Terzhinan not conducted in connection with low systemic absorption.

Testimony

Treatment of vaginitis, caused by sensitive microorganisms:

- Bacterial vaginosis;

- Bacterial vaginitis, caused by a banal or conditionally rod-pyogenic microflora;

- Vaginal trichomoniasis;

- Vaginitis, caused by fungi of the genus Candida;

- Mixed vaginitis.

Preventing vaginitis:

- Before gynecological operations;

- Before birth or abortion;

- Before and after the IUD;

- Before and after the cervix diathermocoagulation;

- Before hysterography.

Dosage regimen

Assign 1 vaginal tab. / day before bedtime. Средняя продолжительность курса терапии – 10 days; when confirmed mycosis

It can be increased to 20 days. Do not stop treatment during menstruation.

Before introduction into the vagina for a tablet to be 20-30 s hold water.

Side effect

Local reactions: редко – чувство жжения, Local irritation (especially early in treatment).

Other: крайне редко – аллергические реакции.

Contraindications

- Hypersensitivity to the drug.

Pregnancy and lactation

Perhaps terzhinan use during pregnancy and lactation (breast-feeding) on indications.

Cautions

It is necessary to carry out the simultaneous treatment of sexual partners at risk of re-infection.

Overdose

Due to the low degree of absorption into the systemic circulation overdose is unlikely.

Drug Interactions

Clinically significant drug interactions Terzhinan drug with other drugs have been identified.

Conditions of supply of pharmacies

The drug is released under the prescription.

Conditions and terms

The drug should be stored at room temperature. Shelf life - 3 year.