Rennes

Active material: Calcium carbonate, Magnesium carbonate
When ATH: A02AX
CCF: Antacids
ICD-10 codes (testimony): K30, R10.1, R12, R14
When CSF: 11.01.04
Manufacturer: BAYER CONSUMER CARE AG (Switzerland)

Pharmaceutical form, composition and packaging

◊ Chewable Tablets White kremovatam with white, square, with concave surfaces, Engraved “Rennie” with both sides, with the smell of menthol.

Excipients: sucrose (475 mg), pregelatinized corn starch, potato starch, talc, magnesium stearate, light liquid paraffin, fresh air freshener, lemon flavor.

6 PC. – blisters (2) – packs cardboard.
6 PC. – blisters (4) – packs cardboard.
6 PC. – blisters (6) – packs cardboard.
6 PC. – blisters (8) – packs cardboard.
6 PC. – blisters (16) – packs cardboard.
12 PC. – blisters (1) – packs cardboard.
12 PC. – blisters (2) – packs cardboard.
12 PC. – blisters (3) – packs cardboard.
12 PC. – blisters (4) – packs cardboard.
12 PC. – blisters (8) – packs cardboard.

◊ Tablets chewable Mint without sugar White kremovatam with white, square, with concave surfaces, Engraved “Rennie” with both sides, with the smell of mint.

Excipients: sorbitol, pregelatinized corn starch, potato starch, talc, magnesium stearate, light liquid paraffin, mint flavor, sodium saccharin.

6 PC. – blisters (2) – packs cardboard.
6 PC. – blisters (4) – packs cardboard.
6 PC. – blisters (6) – packs cardboard.
6 PC. – blisters (8) – packs cardboard.
6 PC. – blisters (16) – packs cardboard.
12 PC. – blisters (1) – packs cardboard.
12 PC. – blisters (2) – packs cardboard.
12 PC. – blisters (3) – packs cardboard.
12 PC. – blisters (4) – packs cardboard.
12 PC. – blisters (8) – packs cardboard.

◊ Chewable Tablets (orange) White kremovatam with white, square, with concave surfaces, Engraved “Rennie” with both sides, with the smell of orange.

Excipients: sucrose (475 mg), pregelatinized corn starch, potato starch, talc, magnesium stearate, Liquid paraffin, orange flavor (Orange oil, maltodextrin, Purified water), sodium saccharin.

6 PC. – blisters (2) – packs cardboard.
6 PC. – blisters (4) – packs cardboard.
6 PC. – blisters (6) – packs cardboard.
6 PC. – blisters (8) – packs cardboard.
6 PC. – blisters (16) – packs cardboard.
12 PC. – blisters (1) – packs cardboard.
12 PC. – blisters (2) – packs cardboard.
12 PC. – blisters (3) – packs cardboard.
12 PC. – blisters (4) – packs cardboard.
12 PC. – blisters (8) – packs cardboard.

Pharmacological action

Antacid medication local action. Contains calcium carbonate and magnesium carbonate, that provide fast and long-lasting neutralizing excess hydrochloric acid gastric juice, thereby providing a protective effect on gastric mucosa.

Achieving therapeutic effect for 3-5 min due to good solubility and high content of calcium.

Pharmacokinetics

Absorption

As a result of the interaction of Rennie^® with gastric juice in the stomach are formed soluble salts of calcium and magnesium. The level of calcium and magnesium absorption of these compounds depends on the dose of the drug. The maximum level of removals – 10% calcium 15-20% Magnesium.

Deduction

A small amount of absorbed calcium and magnesium is excreted by the kidneys. In the gut of the soluble salts are formed insoluble compounds, that excretiruyutza with faeces.

Pharmacokinetics in special clinical situations

If the kidney function, the concentration of calcium and magnesium in plasma may increase.

Testimony

Symptoms, associated with high acidity gastric juice and reflux oesophagitis (in t. no. caused by errors in diet, taking drugs, alcohol abuse, coffee, nicotine):

- Heartburn;

is belching;

-recurrent pain in the stomach;

is a feeling of fullness or heaviness in the area epigastralna;

- Flatulence;

-neuralgia.

Neuralgia pregnant.

Dosage regimen

Adults and children over the age of 12 years when symptoms 1-2 tab. should razjewati (or to keep the mouth until resorption). If necessary, you can repeat the dose through 2 no. The maximum daily dose -16 tab.

Side effect

Allergic reactions: in very rare cases, there may be a rash, angioedema, anaphylactic reactions.

While respecting the recommended doses of the drug well tolerated.

Contraindications

- Severe renal insufficiency;

- Hypercalcemia;

- Hypersensitivity to the drug.

Pregnancy and lactation

When used in recommended doses the drug poses no hazard to the fetus or child.

Cautions

Patients with impaired kidney function should not take the drug at high doses for a long time.

In appointing the drug patients with impaired kidney function should regularly monitor the concentration of magnesium and calcium in serum.

Application Of Rennie^® in high doses can increase the risk of kidney stones.

If necessary, the appointment of the drug patients diabetes, it should be borne in mind, what 1 Tablet Rennie^® with the smell of oregano and 1 Tablet Rennie^® with the smell of oranges containing 475 Sucrose mg.

1 Tablet Rennie^® Mint contains 400 mg of sorbitol and saccharine and can be prescribed to patients with diabetes mellitus.

In the case of failure of treatment the patient should see a doctor.

Effects on ability to drive vehicles and management mechanisms

The drug does not affect the ability to manage vehicles and other activities, require high concentration and speed of psychomotor reactions.

Drug Interactions

Medicines should be taken for 1-2 hours before or after taking antacid medications.

While applying Rennie^® reduces the absorption of tetracycline antibiotics, fluoroquinolones, Phosphates.

Anticholinergic drugs increase and prolong the action of Rennie^®, slowing gastric emptying.

While applying Rennie^® reinforces the effect of Sulfadiazine, levodopa, acetylsalicylic acid and nalidixic acid.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children at or above 25 ° C. Shelf life pill chewing with the smell of oregano and Mint chewable tablets- 5 years, tablets chewable Orange Scented – 3 year.