Pyritinol
When ATH:
N06BX02
Characteristic.
White or white with a slightly yellowish white crystalline powder. Easily soluble in water, slightly soluble in alcohol.
Pharmacological action.
Nootropic, stimulating metabolism in the CNS, improving brain blood circulation.
Application.
Confusion and depression (presenile, senile, affective insanity, anxiety-depressive syndrome, erased state polymorphic subdepressive, psihoastenopodobnye and hypochondriacal disorder), psycho-organic syndrome, asthenic condition, adinamija, neurosis disorders of organic origin, vasoneurosis, migraine, traumatic and vascular encephalopathy, cerebral arteriosclerosis, consequences of cerebral circulatory disorders, neuroinfection and intoxications, neyrolepticheskaya therapy (as a proofreader), dementia (Primary degenerative, vascular and mixed origin), memory impairment, thinking, decreased ability to concentrate, premature onset of fatigue, shortage of motives and motivations, affective disorders; children-mental retardation, tserebrastenicheskom disorder, mental retardation, encephalopathy.
Contraindications.
Hypersensitivity (incl. to penicillamine), psychomotor agitation, epilepsy, high state of readiness for convulsions, liver and / or kidney failure, changes in peripheral blood, diffuse connective tissue disease, myasthenia, pemphigus.
Restrictions apply.
Pregnancy, lactation.
Pregnancy and breast-feeding.
Application of pregnancy is possible only under strict conditions in the case, when the intended benefits to the mother outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.
Side effects.
From the nervous system and sensory organs: sleep disturbance, hypererethism, irritability, psychomotor agitation (children), headache, dizziness, fatiguability, anorexia, taste disturbance.
From the digestive tract: nausea, vomiting, diarrhea, transient increase in transaminases, cholestasis.
Other: arthralgia, lichen planus, pemfigoidnye skin reactions, alopecia, allergic reactions (rashes on the skin and mucous membranes, itch, hyperthermia).
Cooperation.
It increases the severity of side effects of penicillamine, drugs and sulfasalazine, gold.
Overdose.
Symptoms: signs of CNS excitation.
Treatment: simptomaticheskaya therapy.
Dosing and Administration.
Inside, 15-30 minutes after eating, last admission no later than 17 no. Adults: by 0.1-0.3 g 2-3 times a day, 0,2-0.6 g/day. The course of treatment - 1-3 months, in some cases — 6-8 months, Refresh course — via 1-6 months. When migraine: prevention is on 0,3 g/day for 2-3 days before the expected attack, cupping — 0,2 g once.
Babies: 1-3 years-0.05-0.1 g/day, 4-10 years-0.1-0.15 g/d, 11-14 years-0.2-0.3 g/day 2-3 reception. The course of treatment - from 2 Sun 2-3 months, repeat the course in 3-6 months.
Precautions.
Do not take in the evening Pyritinol.
It should be taken into account, In patients with concomitant rheumatoid arthritis and other chronic diseases of the joints, the following adverse reactions: proteinuria, nephrotic syndrome; stomatitis; eozinofilija, thrombocytopenia, leukopenia, agranulocytosis, increase the level of antinuclear antibodies in the blood; dyspnoea, muscular weakness, paraesthesia, polimiozit, hepatitis, hematuria, appearance in blood cells LE-.
Cooperation
Active substance | Description of interaction |
Penicillamine | FMR. Against the background of increased risk of Pyritinol and severity of side effects. |
Sulfasalazine | FMR. Against the background of increased risk of Pyritinol and severity of side effects. |