Molsidomin

When ATH:
C01DX12

Characteristic.

The white crystalline powder.

Pharmacological action.
Antianginalnoe, vasodilator, venodilatiruyuschee, antiagregatine, analgesic.

Application.

CHD: prevention and relief of angina attacks (in case of intolerance or lack of efficacy of nitrates), acute myocardial infarction (after stabilization of hemodynamic parameters); pulmonary hypertension, chronic pulmonary heart, chronic congestive heart failure (combination therapy).

Contraindications.

Hypersensitivity, severe hypotension (Sad below 100 mmHg.), cardiogenic shock, decrease in end-diastolic pressure in the left ventricle and central venous pressure, collapse, pregnancy (I trimester), lactation.

Restrictions apply.

The acute stage of myocardial infarction, hepatic failure, severe renal insufficiency, advanced age.

Pregnancy and breast-feeding.

When pregnancy (especially in the I trimester) application is possible only in case of absolute necessity, the expected benefit to the mother outweighs the potential risk to the fetus. At the time of dosing is recommended to stop breast-feeding.

Side effects.

From the nervous system and sensory organs: headache, dizziness, lethargy.

Cardio-vascular system and blood (hematopoiesis, hemostasis): low blood pressure, collapse, redness of the skin.

From the digestive tract: nausea, diarrhea.

Other: decreased appetite, allergic skin reactions, bronchospasm.

Cooperation.

It enhances the effect of antihypertensive drugs. Alcohol enhances the effect of the drug.

Overdose.

Symptoms: severe headaches, gipotenziya, tachycardia.

Treatment: symptomatic.

Dosing and Administration.

Inside, after meal, on 1-2 mg 2-3 times a day, a maximum of 6 once a day. Retardnye form — 1-2 times a day. Mild attack of angina — sublingually 1-2 mg.

Precautions.

Carefully (under the control of blood pressure) allocating the first dose, tk. possible intense headaches and excessive hypotension with loss of consciousness, especially in patients with initial hypotension, umenyshennыm OCK. In patients with hepatic insufficiency, severe renal insufficiency, in the elderly drug is prescribed with caution, treatment is initiated with low doses. Drug treatment in the acute phase of myocardial infarction is possible only under the condition of constant medical supervision and control of blood pressure, Heart rate and central hemodynamics. At the time of treatment should be deleted alcohol intake. Early treatment is prohibited to drive and engage in potentially hazardous activities, require attention and speed of reaction.

Cooperation