MAHNEROT
Active material: Magnesium Orotate
When ATH: A12CC09
CCF: Magnesium-containing preparation
ICD-10 codes (testimony): E61.2, E78.5, I21, I49, I50.0, I70, R25.2
When CSF: 01.11.02.02.01
Manufacturer: Worwag PHARMA GmbH & Co. KG (Germany)
Pharmaceutical form, composition and packaging
◊ Pills white, with a facet and Valium on the one hand.
1 tab. | |
Magnesium orotate dihydrate | 500 mg, |
incl. magnesium | 32.8 mg |
Excipients: carmellose sodium, corn starch, colloidal silicon dioxide, lactose monohydrate, magnesium stearate, sodium cyclamate, povidone K30, talc, microcrystalline cellulose.
10 PC. – packings Valium planimetric (2) – packs cardboard.
10 PC. – packings Valium planimetric (5) – packs cardboard.
Pharmacological action
The preparation of magnesium. Magnesium is an essential macroelement. Needed for many energy processes, is involved in the metabolism of proteins, fat, carbohydrates and nucleic acids.
Magnesium is involved in neuromuscular excitation, inhibiting neuromuscular transmission. Of particular interest is magnesium as a natural physiological calcium antagonist. Magnesium controls the normal functioning of the cells of the myocardium; participates in the regulation of contractile function of the myocardium. In stressful situations, displayed an increased amount of free ionized magnesium, therefore the added amount of magnesium improves resistance to stress.
The preparation Magnerot® It includes orotic acid, which promotes cell growth, is involved in the metabolism. Besides, orotic acid is necessary for fixation of magnesium ATP in the cell and displays its action.
Pharmacokinetics
The data on the pharmacokinetics Magnerot® not provided.
Testimony
In the combined therapy and prevention of the following diseases:
- Myocardial infarction;
- Congestive heart failure;
- Arrhythmia, caused by magnesium deficiency;
- Spastic conditions (incl. angiospazm);
- Atherosclerosis;
- Dyslipidaemia.
Dosage regimen
Assign inside of 2 tab. 3 times / day for 7 days, then – by 1 tab. 2-3 times / day every day. The duration of treatment – no less 4-6 weeks. The question of carrying out repeated courses of treatment solved individually.
At nocturnal leg cramps I recommend taking the evening 2-3 tab. product.
The tablets should be taken with a little liquid.
Side effect
From the digestive system: unstable stool and diarrhea (while taking the drug at high doses), which usually runs alone at lower doses.
Other: allergic reactions.
Contraindications
- Urolithiasis disease;
- Renal dysfunction;
- Liver cirrhosis with ascites;
- Up to 18 years (efficacy and safety have not been established);
- Hypersensitivity to the drug.
Pregnancy and lactation
Perhaps the use of magnerot® Pregnancy and lactation (breast-feeding) on indications, since these periods need for magnesium is significantly increased. If the content is not balanced, it can lead to serious complications, incl. miscarriage.
Cautions
Mahnerot® It can be used for a long time. It should be taken into account, that a deficiency of magnesium in the body can cause gastrointestinal diseases; consumption of food with a reduced content of magnesium; Saint Martin's evil (due to the reduction of magnesium reabsorption in the renal tubules and increased excretion of magnesium from the body); taking certain medications (oral contraceptives, Diuretic, muscle relaxants, GCS, insulin); states, requiring increased intake of magnesium (gipodinamiя, stress, pregnancy).
Overdose
Symptoms: possibly increasing incidence described side effects.
Treatment: symptomatic therapy.
Drug Interactions
Drug Interactions drug Magnerot® not disclosed.
Conditions of supply of pharmacies
The drug is resolved to application as an agent Valium holidays.
Conditions and terms
The drug should be stored at temperatures above 25 ° C, out of reach of children. Shelf life – 5 years.