Holinergical urticaria – what is this, treatment of disease. Symptoms and prevention of the disease Holinergical urticaria

Холинергическая крапивница – что это за болезнь? Холинергическая крапивница – кожный дерматит аллергического характера, caused by the human immune system sensitivity to mediatoru acetylcholine.

Characteristic education is the manifestation of the integuments blisters pale-pink, very itch.

Holinergical urticaria: the cause of the

Provokes holinergicescoy urticaria neurotransmitter acetylcholine. By acetylcholine, implemented regulation of neuromuscular activity of the human body.

The main condition for the development of genetic predisposition is urticarial holinergicescoy person to allergies and increased acetylcholine production organism. Sverhproducirovanie acetylcholine provokes exacerbations of chronic diseases, in particular, diseases of the GASTROINTESTINAL TRACT, vascular and endocrine systems

Factors, that provoke the development of disease:

• stressful situations and emotional overload;
• increased sweating as a consequence of the characteristics of the organism or when high physical loads;
• When overheated (a long stay in a steam room, hot tub, etc.).

Symptoms holinergicescoy urticaria

On the skin of the patient are formed blisters reddish tint in the middle and richer to the edges, diameter 3-4 mm, on your mind remind nettle Burns. In addition to the external characteristic manifestations, there are additional signs:

• the affected areas there is intense itching and burning;
• patient's body temperature rises;
• nausea may occur, vomiting, diarrhea.

A distinctive feature of most types of allergic reactions, is that, that define holinergicescuu hives is not difficult. For diagnostic use provocative trial (in the body of the patient injected synthetic substance similar in composition with acetylcholine), as well as using confirmatory factor (the patient's hands dipped in hot water). Diagnosis is carried out in case of bubbles and swellings after provocative samples. Additionally carry out blood tests for allergens, in order to eliminate other factors causing hives.

Holinergical urticaria: diagnostics

For correct diagnosis applied skin test, to do this, the patient is injected drug, chemical composition, identical to acetylcholine.

For the skin test is used karboholin 0,01 ml, its vvodjatpodkozhno. After 15-20 minutes to assess the size of the spots, If the spot size to 7-8 mm is a variant of the rules, Allergic stain over 15 mm indicates holinergicescuu cause lesions on the skin.

Also, for diagnostic purposes, используют провоцирующие факторы – искусственная стимуляция аллергической реакции. For this purpose it is necessary to, What would a patient omitted at your hands in the water a few minutes, temperature equals 42-45° c. If the cause of the lesions is holinergical urticaria, sometime during the 2-3 minutes in the hands of the patient will appear blisters, skin redness and swelling is formed.

The patient should pass a blood test for allergens, that would exclude other factors, that could cause rashes.

An important factor in the diagnosis of this disease is examined by specialized professionals: endocrinologist, gastroenterologist, cardiologist and t. P. Because the holinergical hives often provokes systemic diseases, and their diagnosis and treatment is necessary in order, to further therapy urticaria was effective.

Holinergical urticaria: types of disease

This classification is not granted.

Holinergical urticaria: patient actions

The patient should consult an allergist, as well as screening at functional specialists.

Treatment holinergicescoy urticaria

Treatment methods include local hives holinergicescoy therapy, the use of gels and ointments. Preparations for the treatment of this disease have extract krasavki and atropine, which is directed at suppressing the activity of acetylcholine. Use antigistaminnah drugs ineffective, because an allergic reaction occurs due to substances, which produces the organism itself.

The choice of means and methods of treating physician determines, because self-treatment may be complications in the form of other allergic reactions. In case of complications, symptoms aggravated by rhinitis, cough, headaches, conjunctivitis. Data manifestations require separate therapies using antigistaminnah drugs and vitamin complexes.

In some cases, allergies can provoke irritability and insomnia, When these symptoms need to corticosteroids and sedation. You must also pass an additional examination and treatment of chronic diseases.

Holinergical urticaria: complications

Not disclosed.

Prevention holinergicescoy urticaria

Those patients, who was diagnosed holinergical urticaria, the following rules must be observed in order to prevent its recurrence:

• completely eliminate from the diet and spicy food spicy, abandon alcohol and hot drinks;
• taking a bath or shower, stick to temperature-the temperature of the water should not exceed 36-37° c;
• You must reduce the amount of stress and normalize a lifestyle;
• with the expected stressful situations (exam, etc.) take a sedative assigned physician;
• timely and correct treatment of viral and bacterial infections;
• When playing sports or during any physical activity, You must abide by this rule: You must stop the physical work before the advent of heavy sweating, perhaps, It is worth to take a break, wash water and relax.