With Grippostad

Active material: Combined preparation
When ATH: N02BE51
CCF: The drug for the symptomatic treatment of acute respiratory diseases
ICD-10 codes (testimony): J06.9, J10, M79.2, R50, R51, R52.0, R52.2
When CSF: 03.02.01.03.01
Manufacturer: STADA Arzneimittel AG (Germany)

Pharmaceutical form, composition and packaging

◊ Capsules hard gelatin, opaque, size №1, yellow cap and white body; contents of capsules – powder from white to yellowish.

Excipients: gelatin, gliceroltristearat, lactose monohydrate.

The composition of the shell capsules: gelatin, water, Titanium dioxide, quinoline yellow, Yellow dye “sunset”.

10 PC. – packings Valium planimetric (1) – packs cardboard.
10 PC. – packings Valium planimetric (2) – packs cardboard.

Pharmacological action

Analgesics, antipyretics combined structure.

Paracetamol has a strong analgesic, antipyretic and mild anti-inflammatory effect.

Xlorfenamin – gistaminovыh blocker H₁-receptors, It has anti-allergic effect, It reduces the permeability of blood vessels of the mucous membranes of the upper respiratory tract, eliminates tearing, itchy eyes and nose.

Ascorbic acid increases the overall resistance of the organism, incl. infection, reduces the permeability of blood vessels.

Caffeine increases the tone of cerebral vessels, It stimulates the heart, It has antispasmodic action, analʹgeziruûŝee enhances effect of paracetamol.

The combination of the components of the drug provides better tolerability symptoms of malaise and fever with the flu and other colds.

Pharmacokinetics

The data on the pharmacokinetics Grippostad C is not provided.

Testimony

- Pain weak or medium intensity (incl. headache, sore throat, neuralgia);

- Fever with the flu, and other infectious and inflammatory diseases of the upper respiratory tract.

Dosage regimen

A single dose of 2 caps. If necessary, the drug can be administered at the same dose every 4-6 no, but not more 3-4 time / day. The maximum daily dose should not exceed 12 caps.

The patient should be warned, With that Grippostad not recommended more 3 days as antipyretic and more 5 days as an analgesic without the supervision of a physician.

Side effect

Allergic reactions: rash, itch, hives; in some cases – hypersensitivity reactions to paracetamol (swelling of the face, Sweating, nausea, suffocation, drop in blood pressure up to shock).

From the digestive system: dry mouth, dyspepsia; Chronic administration of high doses – abnormal liver function.

From the urinary system: difficulty urinating; Chronic administration of high doses – impairment of renal function.

From the hematopoietic system: a rare - thrombocytopenia, leukopenia.

Contraindications

- Expressed human liver;

- Expressed by the human kidney;

- The absence of a genetic glucose-6-phosphate dehydrogenase;

- Blood disorders;

- Zakrыtougolynaya glaucoma;

- Benign prostatic hypertrophy with the formation of residual urine;

- Heart rhythm disturbances;

- Severe hypertension;

- Pregnancy;

- Lactation (breast-feeding);

- Childhood and adolescence up 15 years;

- Hypersensitivity to the drug.

Pregnancy and lactation

The drug is contraindicated during pregnancy and lactation.

Cautions

Caution should be used Grippostad C in patients with impaired liver and kidney function, when Gilbert's syndrome (constitutional hyperbilirubinemia).

To avoid liver toxicity when using the drug, patients should avoid alcohol. It should not be prescribed to patients with chronic alcoholism.

It is not recommended to use the drug on a background of Grippostad With the simultaneous administration of other drugs, containing paracetamol or other non-narcotic analgesics and NSAIDs (incl. Metamizole, acetylsalicylic acid, Ibuprofen), and amid simultaneous reception barbiturates, antiepileptics, rifampicin, levomicetina.

Monitoring of laboratory parameters

Prolonged (more 5 days) use of the drug is necessary to monitor patterns of peripheral blood and functional state of the liver.

Effects on ability to drive vehicles and management mechanisms

Some patients receiving Grippostad C may be accompanied by a feeling of mild fatigue, changing the speed of psychomotor reactions, deterioration of driving ability.

Overdose

Symptoms: nausea, vomiting, epigastric pain, Sweating, tachycardia, arrhythmia, pale skin; through 1-2 d determined by the symptoms of liver injury; in severe cases develop liver failure and coma.

Treatment: gastric lavage within the first 4 no, appointment of adsorbents; symptomatic therapy.

Drug Interactions

With simultaneous use of paracetamol (which is part of the preparation Grippostad With) medicine, inducing liver enzymes (Some hypnotics and anticonvulsants, rifampicin, ethanol), usilivaetsâ gepatotoksičnostʹ paracetamol.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

List B. The drug should be stored at temperatures above 25 ° C. Shelf life – 5 years.