Furazidin
When ATH:
J01XX00
Characteristic.
Yellow or orange-yellow crystalline powder, odorless, bitter taste. Practically insoluble in water and alcohol.
Pharmacological action.
Antimicrobial, Antibacterial, bacteriostatic.
Application.
For intake - an infection of the urogenital tract (incl. after surgery: pyelonephritis, cystitis, uretrit). For topical administration - cystitis, uretrit, vulvovaginitis, primary and secondary infected wounds, burns, Fistula, keratit, conjunctivitis.
Contraindications.
Hypersensitivity, end-stage renal disease, deficiency of glucose-6-fosfatdegidrogenazы, Age less 1 Months.
Restrictions apply.
Chronic renal failure, nervous system diseases.
Side effects.
Dyspeptic syndrome (anorexia, nausea, vomiting), liver dysfunction, CNS (dizziness, polyneuritis). Allergic reactions (itching, papular rash).
Cooperation.
Funds, alkalizing urine, reducing effect (accelerate urinary excretion), acidifying the urine, - Increase. Aminoglycosides and tetracycline enhance antimicrobial activity. It increases blood oppression against the backdrop of chloramphenicol and ristomycin.
Overdose.
Manifested acute toxic hepatitis, Neuro- (polyneuritis) and hepatic lesions.
Dosing and Administration.
Inside, after meal, drinking plenty of fluids, - 100-200 mg 3 times a day for 10-14 days, if necessary - repeatedly at intervals of 10-14 days between courses. Locally - For douching and washing solution is used (1:13000) physiological solution; in ophthalmology - In an aqueous solution of similar concentration (by 2 drops in each eye 4-6 times a day).
Precautions.
To prevent neuritis with prolonged use must be combined with B vitamins.
Cooperation
Active substance | Description of interaction |
Tetracycline | FMR: synergism. Strengthens (mutually) effect. |
Chloramphenicol | FMR. Against the background of increased risk furazidina bone marrow suppression. |