Etamsylate
When ATH:
B02BX01
Characteristic.
Hemostat.
White with pink tinge crystalline powder. Easily soluble in water, soluble in alcohol.
Pharmacological action.
Hemostatic, angioprotektivnoe.
Application.
Prevent and stop bleeding: parenchymal and capillary bleeding, incl. traumatic, in surgery for operations on the well vascularized organs and tissues, for surgical interventions in the dental (removal of cysts, Granules, extraction of teeth and others.), Urological (prostatectomy and others.), ophthalmological (keratoplasty, cataract surgery, protivoglaukomatoznye surgery and other surgeries), ENT practice (tonsillectomy, microsurgical operations on the ear, and others.); intestinal, kidney, pneumorrhagia, Metro- fibroids and menorrhagia at, bleeding secondary to thrombocytopenia and thrombocytopathy, hypocoagulation, hematuria, intracranial hemorrhage (incl. in neonates and premature infants), epistaxis with hypertension, Medicinal bleeding (unless caused anticoagulant), gemorragicheskiy vasculitis, gyemorragichyeskii diatyez (incl. idiopathic thrombocytopenic purpura, Jurgen von Willebrand, trombocytopathies), vascular diseases with hemorrhagic syndrome, diabetic microangiopathy (gemorragicheskaya diabeticheskaya retinopathy, repeated bleeding in the retina, hemophthalmus).
Contraindications.
Hypersensitivity, thrombosis, thromboembolism, acute porphyria, hematological malignancies in children.
Restrictions apply.
Haemorrhages on the background of anticoagulants.
Pregnancy and breast-feeding.
When pregnancy is possible, if the effect of therapy outweighs the potential risk to the fetus (etamzilata safety of pregnancy has not been established). At the time of treatment should stop breastfeeding.
Side effects.
Dizziness, headache, facial flushing, paresthesia of the lower limbs, Sad decline, heartburn, severity of epigastric, allergic reactions.
Cooperation.
Pharmaceutical incompatible (in the same syringe) with other drugs. Administering a dose of 10 mg / kg 1 h to dextran (average molecular weight of 30-40 thousand. Yes) prevents antiagregatine action (after the introduction of dextran has no hemostatic effect). Acceptable combination with aminocaproic acid, menadione sodium bisulfite.
Dosing and Administration.
Inside, I /, / m. The mode set individually depending on the evidence. Inside - the average single dose for adults 250-500 mg (if necessary, it can be increased to 750 mg) 3-4 Times daily. In / in or / m - the optimal daily intake for adults 10-20 mg / kg, divided by 3-4 injections. Children prescribed at a dose of 10-15 mg / kg / day for 3-4 hours.
The solution for injection can be administered topically (tooth extraction and others.) - Impregnated sterile swab and applied to the wound.
In ophthalmic practice - subkonъyunktyvalno in the form of eye drops retrobulbarno.
Precautions.
Care should be taken when appointing patients with thrombosis or thromboembolism.
When hemorrhagic complications, associated with an overdose of anticoagulants, it is recommended to use specific antidotes.
Use in patients with impaired coagulation parameters possible, but it should be complemented by conducting PM, address the identified deficiency or defect of factors coagulation.
