Doksilamin

When ATH:
R06AA09

Characteristic.

Blocker H₁-histamine receptors from the group ethanolamines.

Pharmacological action.
Snotvornoe, sedation, antiallergic.

Application.

Infringement sleep; allergic reactions, itching; colds and coughs (in combined preparations).

Contraindications.

Hypersensitivity, zakrыtougolynaya glaucoma, prostatic hyperplasia, urination disorders of various origins, pregnancy, lactation, Age to 6 years (as antihistamine drugs), to 15 years (as sedative-hypnotics).

Pregnancy and breast-feeding.

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Side effects.

Daytime sleepiness, slackness, dry mouth, Parez akkomodacii, constipation, urinary retention.

Cooperation.

Strengthens (mutually) deprimiruyuschee influence of barbiturates, benzodiazepines, klonidina, Opioid analgesics, neuroleptics, ethanol, etc.. Mr. Anticholinergics increase the risk of anticholinergic side effects (dry mouth, urinary retention).

Overdose.

Symptoms: daytime sleepiness, depression, anxiety, dystaxia, tremor, athetosis, convulsions, coma with kardiorespiratornыm kollapsom; midriaz, facial flushing, hyperthermia.

Treatment: symptomatic, If necessary, the appointment protivosudorozhnykh funds, IVL.

Dosing and Administration.

Inside. If insomnia is for 15-30 min before bedtimes for 7.5-30 mg, older people-to 7.5-15 mg; treatment to 2 Sun. When allergic reactions — in one dose to 25 mg every 4-6 h, The maximum daily dose - 150 mg.

Precautions.

Should not be used during the drivers of vehicles and people, skills relate to the high concentration of attention. Be careful when nighttime awakenings in patients receiving the drug (possible confusion or dizziness). At the time of treatment should abandon admission alcohol.

Cautions.

Subject to a low-salt diet should be considered, that effervescent Tablet contains 484 mg of sodium bicarbonate.