Dexketoprofen

When ATH:
M01AE17

Characteristic.

NSAIDs. Dexketoprofen trometamol - vodorastvorimaâ salt of the S-enantiomer of ketoprofen.

Pharmacological action.
Analgesic, anti-inflammatory, pyretic.

Application.

Painful syndrome of mild to moderate intensity of acute and chronic inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, Spondylitis, arthrosis, osteochondrosis); menstrual pain, and toothache.

Contraindications.

Hypersensitivity (incl. to other NSAIDs), gastric ulcer and duodenal ulcer, gastrointestinal bleeding or other active bleeding, bleeding tendency, therapy antikoagulyantami, gastrointestinal diseases (Crohn's disease, nespetsificheskiy yazvennыy colitis), bronchial asthma (incl. history), severe heart failure, kidney and / or liver failure, pregnancy, breastfeeding.

Pregnancy and breast-feeding.

Contraindicated during pregnancy and breastfeeding due to lack of sufficient data, confirming the safety of.

Side effects.

From the digestive tract: heartburn, abdominal pain, rarely - erosive and ulcerative lesions of the gastrointestinal tract.

From the nervous system and sensory organs: headache, dizziness, nervousness, sleep disturbance, paresthesia.

Cardio-vascular system and blood (hematopoiesis, hemostasis): heartbeat, increased blood pressure; rarely - a violation of the blood picture.

With the genitourinary system: rarely - renal dysfunction.

Allergic reactions: skin rash, bronchospasm.

Other: chills, swelling of the extremities, photosensitivity.

Cooperation.

In a joint application with other analgesic and anti-inflammatory drugs - strengthening action. While the use of anticoagulants, Li drugs⁺, metotreksatom, phenytoin, sulfonamides - increased side effects.

Overdose.

Treatment: gastric lavage, simptomaticheskaya therapy.

Dosing and Administration.

Inside. The mode set individually, depending on the type and intensity of pain, the average recommended dose - 12,5 mg 1-6 times a day at intervals of 4-6 hours between meals or 25 mg 1-3 times a day with an interval between doses 8 hours no more than 3-5 days. The maximum dose - 75 mg / day; seniors, patients with impaired liver or kidney function - no more 50 mg per day.

Precautions.

Caution must be exercised in the appointment of the elderly, children, allergies, systemic connective tissue diseases and disorders of hematopoiesis. C caution is used in conjunction with other analgesic and anti-inflammatory drugs, preparations, which reduce blood clotting, lithium preparations, metotreksatom, phenytoin and sulfonamides. Not recommended for use during the drivers of vehicles and people, skills relate to the high concentration of attention.

Not intended for long-term treatment.