IZOFRA

Active material: Framycetin
When ATH: R01AX08
CCF: Antibacterial drug for local use in ENT practice
ICD-10 codes (testimony): J00, J01, J31, J32, Z29.2, Z29.8
When CSF: 06.05.04
Manufacturer: Laboratoires Bouchara-RECORDATI (France)

DOSAGE FORM, COMPOSITION AND PACKAGING

Spray nazalynыy 1.25% 1 ml
framycetin sulfate 12.5 mg (8 th. ME)

Excipients: metilparagidroksiʙenzoat, sodium chloride, lemon acid, water distillirovannaya.

15 ml – plastic bottles (1) Included spray – packs cardboard.

 

Pharmacological action

Aminoglycoside antibiotic for topical use in otorhinolaryngology. Effective bactericidal. It is active against Gram-positive and Gram-negative bacteria, causing the development of infectious processes in the upper respiratory tract.

 

Pharmacokinetics

Research pharmacokinetics Izofra not conducted in connection with low systemic absorption.

 

INDICATIONS

In the combined therapy in infectious and inflammatory diseases of the upper respiratory tract, including:

- Rhinitis;

- Rinofaringitы;

- Sinusitis (in the absence of damage to walls);

Prevention and treatment of inflammatory processes after surgery.

 

DOSAGE

Adults appoint 1 injection into each nostril 4-6 time / day.

Babies appoint 1 injection into each nostril 3 times / day.

The average duration of therapy – 7 days.

By drinking a bottle should be kept in the upright position.

 

SIDE EFFECT

Allergic reactions: in a few cases – cutaneous manifestations.

 

CONTRAINDICATIONS

- Hypersensitivity to framycetin and other antibiotics of the aminoglycoside.

 

Pregnancy and lactation

Adequate and well-controlled clinical studies safety of the drug Izofra during pregnancy and lactation (breast-feeding) not performed.

 

Cautions

If during the 7 days of treatment with a therapeutic effect is weak or absent, the drug should be abolished.

 

OVERDOSE

Due to the low degree of absorption into the systemic circulation overdose is unlikely.

 

Drug Interactions

No clinically significant drug interactions Izofra with other drugs have been identified.

 

Conditions of supply of pharmacies

The drug is released under the prescription.

 

TERMS AND CONDITIONS OF STORAGE

The drug should be stored at temperatures above 25 ° C. Shelf life – 3 year.